@article{ricky_Silitonga_2019, title={Hypoglycemic Activity of Extract Leaf and Root Plant of Jombang (Taraxacum Officinale) in Alloxan-Induced Diabetic Wistar Male Rats}, volume={7}, url={https://jurnal.unai.edu/index.php/isc/article/view/814}, DOI={10.35974/isc.v7i1.814}, abstractNote={<p>Diabetes mellitus (DM) is a serious health problem worldwide, World Health Organization<br>(WHO) declared Indonesia takes the fourth place in the DM problem. To overcome this<br>problem, a synthesis drug and medicines have been produced. But production from this<br>medicine has side effects and require a lot of money for it, while many try to find a solution<br>to this disease. There are plants that can help in lowering blood glucose and that is Jombang<br>as we known as dandelion. Because of this plant ability, this research is made. The purpose of<br>this study is to obtain accurate data for lowering white rat’s blood glucose from 1 g extract of<br>leaf and root as determined volume is 0.4 ml, 0.6 ml, and 0.8 ml from leaf extract each<br>contains 0.65 g, 0.97 g, and 1.29 g and root extract each contains 0.77 g, 1.15 g, and 1.54 g<br>weight wet of herbs. This study uses True Experimental Design, 22 male rats are divided into<br>five groups: Negative Control (Group I), Positive Control (group II), Experiment I (group<br>III): Rats were induced by alloxan and given extracted jombang leaves orally as much as 0.4<br>ml (0.65 gram), 0.6 ml (0.97 gram), and 0.8 ml (1.29gram), Experiment II (group IV): Rats<br>were induced by alloxan and given extracted jombang roots orally as much as 0.4 ml (0.77<br>grams), 0.6 ml (1.15 grams) and 0.8 ml (1.54 grams) and Experiment III (Group v): Rats<br>were induced by alloxan and given extracted as much mixture of leaves and roots of Jombang<br>0.4 ml (0.71 gram), 0.6 ml (1.06 gram) and 0.8 ml (1.42 gram). Treatment started from day 6<br>to day 15 and administered twice a day every 12-hour. The measurement of data was<br>collected on day 6, 9, 12, and 15. The data obtained is analyzed with logistic regression,<br>ANOVA multivariate followed by Duncan’s multiple range test. The result showed that the<br>volume of group leaf extract, robot extract and the mixture of leaf and root extract 0.4 ml</p> <p>(0.65 g), 0.6 ml (0.97 g), and 0.8 ml (1.29 ml) can reducing blood glucose levels in alloxan-<br>induced rats at the end of the Study. The best volume of extract in lowering blood glucose is</p> <p>0.4 ml (1.42 g) mixture of leaf and root extracts of Jombang.</p>}, number={1}, journal={Abstract Proceedings International Scholars Conference}, author={ricky, donn richard and Silitonga, Mettison M.}, year={2019}, month={Dec.}, pages={1855-1870} }