Antibacterial Activity of Psidium guajava L. var. pomifera (Red Guava) and Psidium guajava L. var. pyrifera (White Guava) Bark Extracts on Gastroenteritis-causing Bacteria

Mary Cyrin Victoria Defino; Renee Jean  Juego; Victoria Beth  Malagar; Khirvey  Rullamas; Lanlaine Tolentino; Ferdinand Mendoza

Authors

Mary Cyrin Victoria Defino Adventist University of the Philippines
Renee Jean Juego
Victoria Beth Malagar
Khirvey Rullamas
Lanlaine Tolentino
Ferdinand Mendoza

Keywords:

Antibacterial Efficacy, Escherichia Coli, Salmonella Typhimurium, Psidium Guajava L. Bark, Bark Extract

Abstract

This study explores the antibacterial efficacy of Psidium guajava L. bark extracts against gastroenteritis-causing bacteria, addressing antibiotic resistance and acute gastroenteritis concerns. While prior research highlights Psidium guajava's effectiveness against bacteria like E. coli, limited attention has been given to its bark extracts for gastroenteritis treatment. Through agar microdilution, the Minimum Inhibitory Concentrations (MIC) of Psidium guajava L. var. pomifera (red guava) and Psidium guajava L. var. pyrifera (white guava) bark extracts against Escherichia coli and Salmonella typhimurium were determined. Results revealed identical MIC values for both red and white guava bark extracts against the tested strains, indicating comparable antibacterial potency. Specifically, the MICs were 3.125 mg/mL for Escherichia coli and 1.563 mg/mL for Salmonella typhimurium. These findings highlight Psidium guajava L. bark extracts as promising antibacterial agents against gastroenteritis, regardless of guava variety. The significance of the results of this study will be of value to pharmaceutical and biotechnology companies along with medical professionals that can proceed with in vivo testing, agricultural practitioners who may use this information in agricultural activities, and future researchers who can improve upon the study.

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