GENOTOXICTY OF MENTAWAN (POIKILOSPERMUM SUAVEOLENS) EXTRACTS USING THE ALLIUM CEPA ASSAY

Jedd Fabroa; Precious Mindac; April Ann Karen Quizon; Merbeth Christine L. Pedro; Orlex B. Yllano; Ephraim Ephraim M. Evangelista; Ferdinand A. Esplana; Neil John V. Vegafria

doi:10.35974/isc.v4i1.1856

Authors

Jedd Fabroa Adventist University of The Philippines
Precious Mindac Adventist University of The Philippines
April Ann Karen Quizon Adventist University of The Philippines
Merbeth Christine L. Pedro Adventist University of The Philippines
Orlex B. Yllano Adventist University of The Philippines
Ephraim Ephraim M. Evangelista Adventist University of The Philippines
Ferdinand A. Esplana Adventist University of The Philippines
Neil John V. Vegafria Adventist University of The Philippines

https://doi.org/10.35974/isc.v4i1.1856

Keywords:

Poikilospermum Suaveoelens,, Genotoxicity, Chromosomal Aberration, Herbal Medicine, Mentawan

Abstract

The use of plants as herbal medicine has been known worldwide. People believe that herbal medicine could treat their illnesses even without an established study. There was no recorded study on the genotoxicity of Mentawan (Poikilospermum suaveolens). Mentawan, a stout and woody climber is considered as an herbal medicine that effectively cure diarrhea, gastritis, and the like. This study investigated the effect of Mentawan leaf extract with the root length, root number, and chromosomal aberration of Allium cepa roots using A. cepa Assay. There were no toxicity symptoms evident on the Allium cepa roots. Analysis of variance showed no significant difference in the root number, root length, and chromosomal aberrations in different concentrations of Mentawan and the control.

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