ALOE VERA LINN GEL DAN GULA DARAH PUASA PADA KLIEN PREDIABETES
Keywords:
Gel lidah buaya, Glukosa darah, PrediabetesAbstract
Aloe Vera Linn, umumnya dikenal sebagai Aloe Vera telah menarik perhatian dunia karena khasiat obatnya yang efektif untuk banyak masalah kesehatan termasuk hiperglikemia. Secara khusus, penelitian ini bertujuan untuk menilai efektivitasnya pada klien prediabetes dalam dua kelompok eksperimen yang berbeda, sebelum dan setelah tujuh hari perawatan yang mendokumentasikan perubahan pada kadar glukosa darah puasa klien. Penelitian ini menggunakan desain eksperimen semu. Pengambilan sampel purposive digunakan untuk memastikan bahwa para peserta memenuhi kriteria penelitian di mana pengacakan dengan casting banyak digunakan dalam membagi peserta menjadi dua kelompok eksperimen dengan 15 peserta untuk setiap kelompok. Penelitian ini membandingkan dua kelompok eksperimen: kelompok pertama yang diobati dengan 100 g Aloe Vera gel per hari, dan kelompok kedua yang diobati dengan 200 g Aloe Vera per hari selama tujuh hari. Asupan gel Aloe Vera 100 g dan 200 g efektif dalam mengurangi kadar glukosa darah puasa para partisipan. Perlu dicatat, gel Aloe Vera 200 g memberikan pengurangan signifikan lebih tinggi dari kadar glukosa darah puasa dibandingkan dengan 100 g Aloe Vera gel. Oleh karena itu, penelitian menunjukkan bahwa gel Aloe Vera efisien sebagai pengobatan dalam mengurangi kadar glukosa darah di antara klien prediabetes. Kata kunci: Gel lidah buaya, glukosa darah, prediabetes
Downloads
References
American Diabetes Association. (2009). Toolkit 1: All about your risk for pre-diabetes, type 2 diabetes, and heart disease. Retrieved from http://professional.diabetes. org/admin/UserFiles/2014%20CMR%20English/All%20About%20Prediabetes%20T2D%20and%20Heart%20Disease.pdf
Babu, P. V., Liu, D., & Gilbert, R. E. (2013). Recent advances in understanding the anti-diabetic actions of dietary flavonoids. J Nutr Biochem. (2013 Nov). 24(11), 1777-89. doi: 10.1016/j.jnutbio.2013.06.003
Bagchi, D., & Preuss, H. G. (2013). Obesity: Epidemiology, pathophysiology, and prevention (2nd ed). United States of America: CRC Press Taylor & Francis Group
Benzie I. F. F., & Wachtel-Galor, S. (2011). Herbal medicine: Biomolecular and clinical aspects (2nd ed). Retrieved from http://www.ncbi.nlm.nih.gov/books/ NBK92773/
Bubols, G. B., Vianna, D. R., Medina-Remón, A., von Poser, G., Lamuela-Raventos, L. M., Eifler-Lima, V. L., & Garcia, S. C. (2013). The antioxidant activity of coumarins and flavonoids. Mini-Reviews in Medicinal Chemistry, 13(3), 1-17.
Choi, H., Kim, S., Son, K., Oh, B., & Cho, B. (2012). Metabolic effects of Aloe Vera gel complex in obese prediabetes and early non-treated diabetic patients: Randomized controlled trial. Nutrition, 29(9), 1110-4. doi: 10.1016/j.nut.2013.02.015
Cowsert, L. M. (2010). Biological activities of acemannan. Retrieved from http://www.symmetrydirect.com /pdf/BioActivofAcemannan.pdf
Fallah H. H., Kianbakht, S., Hajiaghaee, R., Afkhami-Ardekani M., Bonakdaran, A., & Hashem, D. F. (2012) Aloe Vera leaf gel in treatment of advanced type 2 diabetes mellitus needing insulin therapy: A randomized double-blind placebo-controlled clinical trial. Journal of Medicinal Plants, 11(43), 9-27.
Gato, T., Takahashi, N., Hirai, S., & Kawada, T. (2010). Various terpenoids derived from herbal and dietary plants function as PPAR modulators and regulates carbohydrates and lipid metabolism. Hindawi Publishing Corporation. PPAR Research. Doi:10.1155/2010/483958
Hamman J. H. (2008). Composition and applications of Aloe Vera leaf gel. Molecules, 13, 1599-1616. DOI: 10.3390/molecules13081599
Heggs, D. (2013). Diabetes the silent killer. Retrieved from http://guardianlv.com/2013/07/diabetes-the-silent-killer/
International Diabetes Federation. (2011). Global Diabetes Plan 2011-2021. Retrieved from http://www.idf.org/sites/default/files/Global_Diabetes_Plan_Final.pdf
Kharwal, H., Panthari, P., Pant, M. K., Kharkwal, H., Kharkwal, A. C., & Joshi, D. D. (2012). Foaming glycosides: A review. IOSR Journal of Pharmacy, 2(5), 23-28.
Kim, K., Kim, H., Kwon, J., Lee, S., Kong, H., Im, S. A., Lee, Y. H., Lee, Y. R., Oh, S. T., Jo, T. H., Park, Y. I., Lee, C. K., Kim, K. (2009). Hypoglycemic and hypolipidemic effects of processed Aloe Vera gel in a mouse model of non-insulin-dependent diabetes mellitus. Phytomedicine. Doi:10.1016/j.phymed.2009.02.014
Kumar, S., Shukla, G. A., & Rao, S. A. (2011). The present status of medicinal plants aspects and prospects. Int. J. Res.Pharmac.Biomed.Sci, 2, 2229-3701.
Mohapatra, S., Rath, B., Maharana, C. S., Pradhan, S., & Tripathy, S. (2013). Hypoglycemic, hypolipidemic properties of Aloe Vera in streptozotocin induced diabetic rats. Int J Biol Med Res, 4(1), 2783-2787.
Murphy, Z. (2013, November). Diabetes: Asia’s ‘silent killer”. BBC News. Retrieved from http://www.bbc.com/news/world-asia-24740288
Pertiwi P.S., & Murwarni H. (2012). Pengaruh pemberian jus lidah buaya terhadap kadar glukosa darah puasa pada wanita prediabetes. Journal of Nutrition College, 1(1), 179-193
Preedy, V. R. (2014). Diabetes: Oxidative stress and dietary antioxidants. USA: Elsevier
Rajeswari R., Umadevi M., Rahale, C. S., Pushpa, R., Selvavenkadesh, S., Sampath- Kumar, K. P., & Bhowmik, D. (2012). Aloe Vera: The miracle plant its medicinal and traditional uses in India. Journal of Pharmacognosy and Phytochemistry, 1(4), 118-124.
Rehman, S-U., Jafri, S. A., Hassan, S., Ahmed, I., & Naim, M. (2011). Study on antidiabetic effect of Aloe Vera extract on alloxan induced diabetic rats. Molecules, 17, 12851-12867, doi:10.3390/molecules171112851
Sari, D. M. (2010). Pemanfaatan lidah buaya (aloe vera) terhadap penurunan kadar gula darah pada penderita diabetes mellitus tipe II di Kecamatan Rantau Selatan Kabupaten Labuhan Batu. Undergraduate Unpublish Thesis. Universitas Sumatra Utara
Sharrif, M. M., & Verma, S. K. (2011). Aloe Vera their chemicals composition and applications: A review. Int J Biol Med Res, 2(1), 466-471.
Sharma, B., Siddiqui, S., Ram, G., Chaudhary, M., & Sharma, G. (2013) Hypoglycemic and hepatoprotective effects of processed Aloe Vera gel in a mice model of alloxan induced diabetes mellitus. J Diabetes Metab, 4, 9. Retrieved from http://dx.doi.org/10.4172/2155-6156.1000303
Singh, U., Singh, P., Rani, B., & Maheshwari, R. (2011). Diverse therapeutic applications of aloe vera: A review. International Journal of Pharmaceutical Development & Technology, 1(1), 25-33.
Sood, N., Baker, W. L., & Coleman, C. I. (2008). Effect of glucomannan on plasma lipid and glucose concentrations, body weight, and blood pressure: Systematic review and meta-analysis. American Journal Clinical Nutrition, 88, 1167-75.
Surjushe, A., Vasani, R., & Saple, D. G., (2008). Aloe vera: A short review. Indian Journal of Dermatology, 53 (4), 163-166.
Yagi, A., Hegazy, S., Kabbash, A., & Wahab, E. A. (2009). Possible hypoglycemic effect of Aloe Vera Linn High molecular weight fractions on type 2 diabetic patients. Saudi Pharmaceutical Journal, 17, 209-215. doi: 10.1016/j.jsps.2009.08.007
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2021 Evelin Malinti, Susy A. Jael
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
